Engler, Peter (Committee chair)
Reisman, Stanley S. (Committee member)
Kristol, David S. (Committee member)
Yellin, Edward L. (Committee member)
Meisner, Jay S. (Committee member)
Date:
1992-08
Keywords:
Heart -- Physiology -- Mathematical models
Cardiovascular system -- Physiology
Availability:
Unrestricted
Abstract:
The study of left ventricular filling in both the normal and the pathological heart is of great importance. A computer model simulation of the heart with emphasis on mitral flow was designed by Meisner in 1986 and implemented in QuickBASIC. This paper discusses how the original program was altered to be able to perform "Parameter vs. Parameter" runs in which it can be observed how varying an input parameter affects output parameters. The output data is then formatted in such a way that it can be used by QUATTRO PRO, a standard spreadsheet package, to yield graphical outputs.
In addition, the original model was implemented in the circuit simulation package PSPICE. This, coupled with the graphics post-processor PROBE that accompanies PSPICE, enables the model to yield higher quality graphs, both P-V loops as well as parameters versus time. This also permits additional information to be gained from the model and offers potential for more easily expanding the model.
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