The New Jersey Institute of Technology's
Electronic Theses & Dissertations Project

Title:	Intermediates for p-acetamidocinnamic ester synthesis
Author:	Fix, William Grayson
View Online:	njit-etd1955-010 (vii, 41 pages ~ 1.9 MB pdf)
Department:	Department of Chemical Engineering
Degree:	Master of Science
Program:	Chemical Engineering
Document Type:	Thesis
Advisory Committee:	Kreps, Saul I. (Committee chair) Frederick, Michael (Committee member) Scheibel, Edward G. (Committee member)
Date:	1955-06
Keywords:	Chemistry, Organic -- Synthesis
Availability:	Unrestricted
Abstract:	After a review of the various methods found in the literature, a series of reactions were selected which were reported to have good yields. Using p-nitrotoluene as a starting material, a simultaneous oxidation and reduction with sodium polysulfide was investigated as a means of making p-aminobenzaldehyde. Experimental procedures and yields were reported, and improved methods of recovery were described. Using p-aminobenzaldehyde from the first reaction, a condensation with malonic acid, in pyridine-piperidine medium, was investigated as a means of preparing p-aminocinnamic acid. A recommended procedure was described, and some suggestions were made concerning the completion of the synthesis of p-acetamidocinnamic esters.