The New Jersey Institute of Technology's
Electronic Theses & Dissertations Project

Title:	Continuum mechanical analysis of space and time dependent deformation pattern of brain with blunt injury
Author:	Miao, Chen
View Online:	njit-etd2016-078 (x, 60 pages ~ 2.7 MB pdf)
Department:	Department of Biomedical Engineering
Degree:	Master of Science
Program:	Biomedical Engineering
Document Type:	Thesis
Advisory Committee:	Pfister, Bryan J. (Committee chair) Chandra, N. (Committee member) Roman, Max (Committee member)
Date:	2016-05
Keywords:	Human brain deformation Traumatic brain iunjury Acceleration impact
Availability:	Unrestricted
Abstract:	Deformation of human brain due to acceleration impact has been widely accepted as the direct connection to the Trauma Brain Injury (TBI). However, the limitation of obtaining deformation data of TBI is a major obstacle to understanding TBI mechanism. This experiment mainly focuses on developing a method to measure deformation pattern of brain with blunt injury. First of all, displacement data of markers on sagittal plane of an injury head model was collected using 3D reconstruction software after an impact test. Second, the displacement data was used to calculate 2D Lagrangian strain tensor and the principal strain. The temporal and spatial results of principal strain under different variables including impact velocity (5 mile/hour, 3 mile/ hour), impact location (crown head, front head) and concentration of gel used to build the brain model (10%, 20%) were compared. The results shown larger strain values within the variables of higher impact velocity, crown head impact location and 10% gel. The spatial location results shown clearly the difference in terms of deformation pattern of different impact locations.