The New Jersey Institute of Technology's
Electronic Theses & Dissertations Project

Title:	In vitro comparison of a new stand-alone anterior lumbar interbody cage device with established fixation techniques
Author:	Chawla, Nitin
View Online:	njit-etd2009-044 (xiv, 111 pages ~ 12.2 MB pdf)
Department:	Department of Biomedical Engineering
Degree:	Master of Science
Program:	Biomedical Engineering
Document Type:	Thesis
Advisory Committee:	Van Buskirk, William C. (Committee co-chair) Heary, Robert F. (Committee co-chair) Foulds, Richard A. (Committee member) Roman, Max (Committee member)
Date:	2009-05
Keywords:	Spinal arthrodesis Lower back pain
Availability:	Unrestricted
Abstract:	Around 70% of the population in the United States experience low back pain at some point of their lives, of these 4% underwent surgical intervention on the lumbar spine to relieve the pain. Spinal arthrodesis, i.e. joint fusion, is beneficial in many cases as the final option for patients suffering from certain types of low back pain (LBP). In order to promote solid fusion across a decompressed spinal segment, interbody spacers/cages are used with and without posterior instrumentation to provide an initial "rigid" fixation of the segment. In this study three fresh/frozen human cadaveric lumbar spines were used. Each lumbar spine was dissected into two Functional Spinal Units (FSUs, L3-L4 and L5-S1) making a total of 6 motion segments. The objective of this study was to evaluate the biomechanical behavior of a new stand-alone anterior lumbar interbody device, by assessing its performance in terms of FSU motion in comparison with the intact FSU and FSUs additional posterior fixation (i.e., facet bolts and pedicle screws). Descriptive statistics and analysis of variance (ANOVA) was used to determine if the differences between the different treatment groups are significant or not. Statistical analysis was also used to determine the contribution of the supplemental fixation for the anterior interbody fusion device (AFD) system.